The upcoming UNCAN-Connect project (2025-2030) will create a decentralised collaborative network for advancing cancer research and innovation. This infrastructure for federated query and analysis will allow cancer researchers and clinicians to identify new biomarkers, stratify patient groups, and design better-targeted therapies by analyzing data patterns on a large scale. The project will use six use cases, focussed on understanding cancer initiation and progression: a) paediatric tumours, b) lymphoid malignancies, c) pancreatic ductal adenocarcinoma, d) ovarian cancer, e) lung cancer, and f) prostate cancer. Each use case will support the development of tools and services for working with FAIR data.
UNCAN-Connect’s main result will be the UNCAN.eu platform, providing various resources such as distributed tools for data access and analysis, a synthetic data generation pipeline, an implementation handbook and recommendations.
CANDLE fundamentally links to UNCAN-Connect since the National Cancer Data Nodes will connect to the UNCAN.eu platform. This provides an essential connection between the Member State and European level, to account for national complexities and differences.
